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Previous studies have indicated that the peak of the quarkonium entropy atthe deconfinement transition can be related to the entropic force which wouldinduce the dissociation of heavy quarkonium. In this paper, we study theentropic force in a rotating hot and dense medium using AdS/CFT correspondence.It turns out that the inclusion of angular velocity increases the entropicforce thus enhancing quarkonium dissociation, while chemical potential has thesame effect. Furthermore, the results imply that the quarkonium dissociateseasier in rotating medium compared to static case.

Entropic destruction of heavy quarkonium in a rotating hot and dense medium from holography