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We present the first direct calibration of strong-line metallicitydiagnostics at significant cosmological distances using a sample at z=0.8 drawnfrom the DEEP2 Galaxy Redshift Survey. Oxygen and neon abundances are derivedfrom measurements of electron temperature and density. We directly comparevarious commonly used relations between gas-phase metallicity and strong lineratios of O, Ne, and H at z=0.8 and z=0. There is no evolution with redshift athigh precision ($\Delta \log{\mathrm{O/H}} = -0.01\pm0.03$, $\Delta\log{\mathrm{Ne/O}} = 0.01 \pm 0.01$). O, Ne, and H line ratios follow the samelocus at z=0.8 as at z=0 with $\lesssim$0.02 dex evolution and low scatter($\lesssim$0.04 dex). This suggests little or no evolution in physicalconditions of HII regions at fixed oxygen abundance, in contrast to modelswhich invoke more extreme properties at high redshifts. We speculate thatoffsets observed in the [N II]/H$\alpha$ versus [O III]/H$\beta$ diagram athigh redshift are therefore due to [NII] emission, likely as a result ofrelatively high N/O abundance. If this is indeed the case, then nitrogen-basedmetallicity diagnostics suffer from systematic errors at high redshift. Ourfindings indicate that locally calibrated abundance diagnostics based onalpha-capture elements can be reliably applied at z$\simeq$1 and possibly atmuch higher redshifts. This constitutes the first firm basis for the widespreaduse of empirical calibrations in high redshift metallicity studies.

Temperature-based metallicity measurements at z=0.8: direct calibration of strong-line diagnostics at intermediate redshift