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Intraspinal injections of magnesium sulphate, in doses which do not affect the respiratory centre or other vital function, are capable of abolishing completely all clonic convulsions and tonic contractions in cases of human tetanus, and experimental tetanus in monkeys. The relaxing effects of the injections may last twenty-four hours or longer. In experimental tetanus in monkeys early intraspinal injections of magnesium salts are capable of retarding the progress and development of the tetanic symptoms.

THE EFFECTS OF INTRASPINAL INJECTION OF MAGNESIUM SALTS UPON TETANUS