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Understanding public vaccine acceptability is critical to preparing for future pandemics. This research investigated Japanese individuals’ willingness to be vaccinated against a hypothetical infectious disease. A conjoint analysis was conducted with a general public panel via an Internet survey agency. Vaccine efficacy, vaccine safety, duration of immunity, and price were chosen as analysis attributes. Each respondent chose from 12 hypothetical scenarios using an online panel. From the 2,155 complete responses, 51,720 results were extracted and analyzed. Higher efficacy, lifetime immunity duration, and fear of the pandemic positively affected willingness to be vaccinated, while higher vaccination price and higher toxicity had negative effects. The number of infected individuals and deaths had no significant impact. A total of 69.2% of the study population reported being willing to receive a vaccine with 100% efficacy, lifetime immunity, and low toxicity and free of charge. This study assessed the preferences for vaccines against infectious diseases with the potential to become pandemics during the COVID-19 pandemic in Japan. This result can influence vaccine-related policy and pandemic preparedness and help governments consider public intention to prepare health communication campaigns that encourage vaccination.

Public preferences and willingness to accept a hypothetical vaccine to prevent a pandemic in Japan: a conjoint analysis