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Investigating mothers’ perceptions of Cerebral Palsy (CP) and the impact of caregiving on family life in Benin, a west-African low to middle-income country (LMIC). In this cross-sectional study we interviewed at their homes 88 mothers of children with CP about their perception of the cause of CP and stigmatization issues. Additionally, they completed the Impact on Family Scale and the Family Support Scale questionnaires. Multinomial and ordinal regressions analyses were used ( p  &lt; 0.05). Most mothers (78%) referred to non-biomedical causes of CP (God’s will or curse). Caregivers with a limited education level were more likely to report non-biomedical beliefs. Only 28% reported having received from physicians an explanation of the causes of CP. Around 38% endorsed neighbors considered their children as cursed, which is a source of stigmatization. Mothers perceived a high impact of caregiving on their family life that correlated with non-biomedical beliefs, low education level, and the severity of CP. There is a need in Benin, and probably in West-African LMICs generally, to shift to a family-centered care system and to inform the public about the root causes of CP to improve social integration of children with CP and decrease the negative impact on their families.Implication for rehabilitationMothers with a limited education level are more likely to report non-biomedical causes of CP in this LMIC;mothers’ level of education and non-biomedical beliefs of causes of CP are associated to a high impact of caregiving on family life in this LMIC;mothers of children with CP in this LMIC do not perceive health-workers helpful. Mothers with a limited education level are more likely to report non-biomedical causes of CP in this LMIC; mothers’ level of education and non-biomedical beliefs of causes of CP are associated to a high impact of caregiving on family life in this LMIC; mothers of children with CP in this LMIC do not perceive health-workers helpful.

Mothers’ perception of cerebral palsy in a low-income country of West Africa: a cross-sectional study