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The objective of this study was to investigate whether oscillometric AS measurements are different in pregnant women with and without preeclampsia (PE). This was a prospective case–control study in singleton pregnancies that had been diagnosed with PE ( n  = 46) versus normotensive controls ( n  = 46) between 2014 and 2019. In the case group, pregnancies complicated by PE were classified as either early-onset (&lt;34 weeks of gestation) or late-onset (≥34 weeks of gestation) PE and subgroup analysis was performed. Pulse wave velocity (PWV), augmentation index (Alx), and Alx at a heart rate of 75 beats per minute (Alx-75) were measured using a brachial cuff-based automatic oscillometric device (Mobil-O-Graph 24 h PWA). In pregnancies complicated by PE, in comparison with normotensive pregnancies, there were significant differences in PWV ( p  ˂ .001), and Alx-75 ( p  ˂ .001). In pregnancies complicated by early-onset PE, in comparison with pregnancies complicated by late-onset PE, there were significant differences in PWV ( p  = .006), and Alx-75 ( p  = .009). There was no significant difference in Alx in either of the analyses. PWV and Alx-75 are higher in pregnancies complicated by PE, in comparison with normotensive pregnancies, as well as in early-onset PE, in comparison with late-onset PE.Key messagesPulse wave velocity is higher in pregnancies complicated by preeclampsia.Augmentation index at a heart rate of 75 beats per minute is higher in pregnancies complicated by preeclampsia.Arterial stiffness assessment is a promising risk-stratification tool for future cardiovascular complications but further studies are required. Pulse wave velocity is higher in pregnancies complicated by preeclampsia. Augmentation index at a heart rate of 75 beats per minute is higher in pregnancies complicated by preeclampsia. Arterial stiffness assessment is a promising risk-stratification tool for future cardiovascular complications but further studies are required.

annals of medicine

Augmentation index and pulse wave velocity in normotensive versus preeclamptic pregnancies: a prospective case–control study using a new oscillometric method