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Objective  (1) Determine the one-week prevalence of moderate to extreme symptoms of anxiety, stress and depression in chiropractic undergraduate students. (2) Determine whether the prevalence varies across gender and year of study.  Participants:  Undergraduate students at the Canadian Memorial Chiropractic College (CMCC).  Methods:  A cross-sectional study was conducted in fall 2017 to measure self-reported symptoms of anxiety, stress and depression using the DASS-21.  Results:  The participation rate was 67.0% (510/766). The one-week prevalence of moderate to extreme symptoms was 19.0% (95% CI: 13.0–25.0) for depression; 32.6% (95% CI: 24.7–40.3) for anxiety and 21.8% (95% CI: 15.6–28.1) for stress. The prevalence of stress varied significantly across gender: 25.4% (95% CI: 20.5–30.3) for females versus 16.3% (95% CI: 11.2–21.3) for males. The one-week prevalence of depressive (24.8%; 95% CI: 17.6–32.0) and anxiety (40.9%; 95% CI: 32.6–49.1) symptoms peaked in second year.  Conclusions:  Self-reported symptoms of anxiety, stress and depression are common in CMCC students.

The prevalence of anxiety, stress and depressive symptoms in undergraduate students at the Canadian Memorial Chiropractic College