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Over the last 50 years Dunedin Study researchers have published more than 1400 peer-reviewed journal articles, books, and reports on many aspects of human health and development. In this 50th anniversary piece we reflect on (i) our historical roots and necessary re-invention through time; (ii) the underpinning principles that have contributed to our success; (iii) some selected examples of high-impact work from the behavioural, oral health, and respiratory domains; (iv) some of the challenges we have encountered over time and how to overcome these; and (vi) review where we see the Study going in the future. We aim to present some of the ‘back story’, which is typically undocumented and oft lost to memory, and thus focus on ‘know-how’. Our hope is to humanise our research, share insights, and to acknowledge the real heroes of the Study – the 1037 Study members, their families and their friends, who have collectively given so much, for so long, in the hope of helping others.

The Dunedin study after half a century: reflections on the past, and course for the future