Open AccessFour heat shock proteins of Drosophila melanogaster coded within a 12-kilobase region in chromosome subdivision 67B.
Author(s) -
Victor G. Corcés,
Robert A. Holmgren,
Robert Freund,
Richard I. Morimoto,
Matthew Meselson
Publication year - 1980
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.77.9.5390
Subject(s) - drosophila melanogaster , biology , melanogaster , genetics , heat shock protein , gene , chromosome , subdivision , x chromosome , chromosome 3 , history , archaeology
Unique coding sequences for four heat shock proteins of Drosophila melanogaster, hsp 28, hsp 26, hsp 23, and hsp 22, are clustered in a 12-kilobase interval at chromosome subdivision 67B. The four genes are not transcribed in the same direction and each gives rise to a separate messenger RNA, with no indication of intervening sequences. Including the present results, the genes for all seven major heat shock proteins of D. melanogaster are now cloned are found to exhibit a variety of patterns of organization at the five loci they occupy.