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Introductory.-The very little knowledge available concerning the iodine metabolism of invertebrates is confined to the occurrence of accumulation of the element in sponges and gorgonians.' It therefore seemed desirable to attack the problem by using I'll in some other organism. Because Drosophila gibberosa is a holometabolous insect, it seemed that valuable information might be obtained which would not only be of interest from the standpoint of iodine metabolism of this fly but would also provide a convenient basis for comparative work on the iodine metabolism of some other insect or arthropod. D. gibberosa, a giant black Mexican species, was sent to this laboratory through the courtesy of Dr. T. Dobzhansky. The size of D. gibberosa as compared with the smaller D. melanogaster is of considerable advantage especially in carrying out the technical side of this problem. Material and Methods.-Radioactive carrier-free iodide was made available to both third instar larvae and adults by stirring 0.2 ml. of a solution of the isotope into approximately 8 ml. of liquid corn meal, molasses and dried Brewer's yeast mixture which had been placed in a creaxmer bottle. The largest quantities of 13l used were 0.2 mc.

The Iodine Metabolism of Drosophila Gibberosa Studied by Means of Radioiodine I 131

The Iodine Metabolism of Drosophila Gibberosa Studied by Means of Radioiodine I ¹³¹