Open AccessDiversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
Author(s) -
Yunfei Cheng,
Gencheng Li,
Christopher J. Smedley,
MarieClaire Giel,
Seiya Kitamura,
Jordan L. Woehl,
Giulia Bianco,
Stefano Forli,
Joshua A. Homer,
John Cappiello,
Dennis W. Wolan,
John E. Moses,
K. Barry Sharpless
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2208540119
Subject(s) - sulfonyl , click chemistry , chemistry , conjugate , combinatorial chemistry , covalent bond , stereochemistry , organic chemistry , mathematical analysis , alkyl , mathematics