English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Significance Adiponectin, a member of the CTRP family of secreted proteins produced by adipose tissue, is thought to function as an endocrine hormone. An unusual feature of adiponectin is that it is present in high concentrations in circulation and thus may have noncanonical endocrine functions. Here we show that adiponectin as well as several other CTRPs and C1q family proteins bind anionic phospholipids, suggesting that their mode of action is opsonization of cells with specific plasma membrane phospholipid compositions. These findings suggest a new perspective on CTRP family function.

Adiponectin and related C1q/TNF-related proteins bind selectively to anionic phospholipids and sphingolipids