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Recently in PNAS, Langergraber et al. (1) presented interesting findings regarding body size and generation times in chimpanzees and gorillas. The authors then combined these data with recent whole-genome estimates of human mutation rate per generation to recalibrate previous estimates of divergence times in great apes and humans. The authors’ divergence estimates are older than previous findings, which reduce the conflict of previous estimates with some contentious older fossil hominins. It is important to have accurate estimations of generation time, but the authors were quick to apply new intergenerational mutation rates to estimates of divergences millions of years ago, without consideration …

Intergenerational mutation rate does not equal long-term evolutionary substitution rate