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The prevalence of gastrointestinal involvement in von Recklinghausen’s disease is frequent (11%–25%) [1] with different types of neurofibroma and juvenile-like polyps [2]. However, the association of von Recklinghausen’s disease with inflammatory fibroid polyps has been only rarely described [3]. We report here the case of a 39-year-old woman with past history of type 1 neurofibromatosis who was referred for hematochezia. Colonoscopy was performed and diagnosed a large pedunculated polyp in the sigmoid with a type Ip shape (Paris classification). Using narrow-band imaging and dual focus magnification (Olympus, Tokyo, Japan), the features of the polyp included an amorphous pit pattern over a large area (Kudo VN). The vascular pattern was patchy avascular areas mixed with large irregular vessels (Sano IIIB) (▶Fig. 1, ▶Fig. 2, ▶Video1). The vascular pattern was present over the whole lesion, without any demarcation line. Using the NICE classification [4], the lesion was classified as type III and was suggestive of a deep submucosal invasive cancer. The lesion was resected en bloc by endoscopic mucosal resection with a large safety margin on the stalk. Pathological examination, after expert discussion (because of the atypical features), concluded a diagnosis of inflammatory fibroid polyp resected totally with safe margins, E-Videos

Colon inflammatory fibroid polyp in a patient with von Recklinghausen’s disease: endoscopic aspect with narrow-band imaging and magnification