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Objective  Transoral odontoidectomy in the treatment of basilar invagination is surgically challenging. Incision of the soft palate significantly increases rostral exposure of the clivus but is associated with a high incidence of speech and swallowing difficulties after surgery. We present a patient suffering from severe compression of the medulla oblongata due to an extreme form of basilar invagination treated successfully with the resection of dens via a transoral nasopharyngeal approach without palatotomy. Setting  Microsurgical endoscopic-assisted odontoidectomy through a transoral epipharyngeal approach was performed with subsequent craniocervical stabilization in a 21-year-old patient suffering from progressive myelopathy due to compression of the medulla oblongata and associated progressive syringomyelia. Results  The 21-year-old man was initially treated with suboccipital craniotomy and duroplasty in another institution. After initial improval he subsequently developed progressive ataxia, dysphagia, a bulbar speech, and weakness of the extremities. Beside ventral compression, he developed a secondary Chiari's malformation and a holospinal syringomyelia. Resection of the dens was successfully accomplished via a microsurgical transoral epipharyngeal endoscopic-controlled odontoidectomy without palatotomy. One week after odontoidectomy, posterior craniocervical stabilization was performed. All preoperative symptoms and signs improved significantly and the patient leads an independent life 4 years after odontoidectomy. On follow-up magnetic resonance imaging (MRI), the syringomyelia completely resolved. Conclusions  Palatotomy with its potential adverse effects can usually be avoided even for the treatment of extreme forms of basilar invagination. The link to the video can be found at: https://youtu.be/CBKE4n94W4g .

Basilar Invagination: Transoral Microsurgical Endoscopically-Controlled Odontoidectomy without Palatotomy in Extreme form of Basilar Invagination