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Seizures are rarely a manifestation of corpus callosum lesions, especially when the lesion is a cavernoma in the genu. Till date only one such case has been reported. Here, we report a 46-year-old male patient who presented with an episode of generalized seizures. Neurological examination was unremarkable. However, a computed tomographic scan revealed a small hemorrhage in the region of the corpus callosum. On further investigations, magnetic resonance imaging and angiography confirmed it to be a cavernoma. The patient was managed conservatively with antiepileptics in view of the location of the lesion and is on regular follow-up. There are no definitive guidelines for management of such patients, and they continue to pose a diagnostic and therapeutic challenge to the practicing neurosurgeon.

Seizures: A Manifestation of Corpus Callosum Cavernoma