English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In a context of rapidly expanding indications for endoscopic ultrasound (EUS)guided procedures, a dedicated forwardviewing linear therapeutic echoendoscope (FV-EUS) has been developed and tested for different clinical indications [1–3]. The frontal endoscopic view combined with the exit of the working channel at the tip of the echoendoscope offers some unique advantages over the standard curvilinear echoendoscope. This has opened up new possibilities for EUS-guided fineneedle aspiration and tissue acquisition (EUS-FNTA) from difficult targets and combined endoscopic/EUS treatment [3, 4]. We have previously described the possibility of using FV-EUS to navigate easily through the colon to reach and sample extracolonic lesions located above the sigmoid tract [4]. We now report the first case of intubation of the ileocecal valve followed by sampling of a distal ileal lesion performed using the FV-EUS. A 68-year-old woman with a 13-year history of ulcerative colitis was found on routine surveillance colonoscopy to have a 1.5cm lesion in the terminal ileum that presented characteristics suggestive of a subepithelial lesion with a normal-appearing overlyingmucosal layer (●" Fig.1). To exclude extrinsic compression, computed tomography was carried out and confirmed the presence of a wall thickening or lesion at the level of the terminal ileum, close to the ileocecal valve. Colonoscopy using the FV-EUS was attempted and was completed up to the cecum. The terminal ileumwas then intubated and, under EUS guidance, a hypoechoic lesion measuring 14×10mm and confined to the thirdwall layer was detected. EUS-FNTAusinga 19-gaugeneedlewas performed (●" Fig.2, ●" Video1) and a tissue sample obtained (●" Fig.3), which revealed a serotonin-secreting neuroendocrine tumor with a Ki67 proliferation index of less than 1%, corresponding to a grade 1 tumor (NET G1). The patient underwent right hemicolectomy, and definitive assessment of the surgical specimen confirmed the diagnosis of a grade 1 serotonin-secreting neuroendocrine tumorwith lymphnode involvement (pT3N1) [5].

Endoscopic ultrasound-guided fine-needle tissue acquisition from a subepithelial lesion in the distal ileum using the forward-viewing echoendoscope