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The article presents the results of research on topical issues of the formation of an effective mechanism of pairwise interaction of the primary participants in the regional innovation subset: that is state, business, universities. A methodical approach to the formation of both componential composition of the regional infrastructure and information-communication platform is proposed. One of the problems is marked by a significant differentiation of socio-economic development of the country’s regions. The negative consequence of the uneven regions’ development is the low efficiency and effectiveness of scientific and educational institutions and congested researchers in regions so it results in preventing practical research outcomes application and development. To eliminate the disproportions an effective mechanism of pairwise interaction of the regional innovation subsystem subjects is proposed. Interaction takes place on the basis of objective resource flows, the number of which is determined in the process of functional matrix building that allows to determine the list of these flows: legal, information and consulting, sales, personnel, material and financial. The conclusion contains a proposal to create an information and consulting platform, as well as to bring into being all the tools of organizational and economic impact for improving the level of infrastructure components development.

Formation of effective mechanism of pairwise interaction of regional innovation subsystem subjects in the conditions of spatial transformation