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Medical image fusion plays an important role in detection and treatment of disease. Although numerous medical image fusion methods have been proposed, most of them decrease the contrast and lose the image information. In this paper, a novel MRI and CT image fusion method is proposed combining rolling guidance filter, structure tensor, and nonsubsampled shearlet transform (NSST). First, the rolling guidance filter and the sum-modified laplacian (SML) operator are introduced in the algorithm to construct the weight maps in non-linear domain, then the fused gradient is firstly obtained by a new weighted structure tensor fusion method, and the fused image is firstly acquired in NSST domain, finally, a new energy functional is defined to constrain the gradient and pixel information of the final fused image close to the pre-fused gradient and the pre-fused image, experimental results show that the proposed method can retain the edge information of source images effectively and preserve the reduction of contrast.

Medical image fusion based on variational and nonlinear structure tensor