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The pollution of aquatic ecosystems by pharmaceuticals is presently recognized as a serious threat. The drug residues may contaminate surface waters via sewage discharges as well as improper disposal of industrial waste. Very few studies focused on the effects of drug pollutants on behaviour of invertebrates. In this study the effects of ibuprofen and venlafaxine on activity of the  Unio tumidus  were studied. Changes in behaviours were analysed at concentrations corresponding to wastewater discharges (3.4, 6.8 and 13.6 μgL −1 ). At dosage of 3.4 μgL −1 , ibuprofen affected the activity time and shell opening level. The reduction in activity was particularly evident during the first few days. The same dose of venlafaxine caused hyperactivity of bivalves during the first few days of exposition. The highest doses (13.6 μgL −1 ) same drugs promoted reduction of activity and shell opening level. Moreover, exposure to these drugs resulted in the reduced water filtering time and hence its purification. The  Unio tumidus  reaction may indicate negative reaction of other aquatic species to the tested drugs.

Effects of ibuprofen and venlafaxine on behavioural parameters in freshwater bivalve Unio tumidus