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Feeding high concentrate diets to ruminants may be detrimental to the ruminal digestion efficiency. The fermentation of readily degradable carbohydrates leads to lactic acid production in the rumen. Lactic acid is produced by several fermentative microbial species such as Streptococcus bovis. When the concentrate level is high, lactic acid, which is normally metabolized by bacterial species such as Megasphaera elsdenii, may accumulate and cause a great decline in ruminal pH, that consequently induces digestive disorders. The positive effect of several microbial additives such as Aspergillus oryzae on in vitro lactate utilization by Selenomonas ruminantium (Nisbet and Martin, 1993, Curr Microbiol, 26, 133-136) and Megasphaera elsdenii (Waldrip and Martin, 1993, J Anim Sci, 71, 2770-2776) and also the efficiency of live yeasts on the stabilization of ruminal pH and other digestive parameters in vivo (Williams et al, 1991, J Anim Sci, 69, 3016-3026) have recently been shown. Nevertheless, the mechanisms of action of these additives remain unclear. The aim of this

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Effects of live cells of Saccharomyces cerevisiae on in vitro lactate utilization by Megasphaera elsdenii and on the interactions between Streptococcus bovis and M. elsdenii grown on glucose