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selectively depresses plasma follicle-stimulating hormone (FSH) concentrations (and therefore probably pituitary FSH secretion) in a dose-dependent manner. As FSH is responsible for promoting follicular growth, the neutralization of endogenous inhibin action by antibodies should therefore maintain or increase FSH secretion and stimulate follicular growth. In experiments to test this, it was observed via laparoscopy, that active immunization against a synthetic peptide fragment of bovine inhibin during the late anoestrous period of ewes resulted in a 90% increase in ovulation rate in the subsequent breeding season and a 35% increase in lambing rate fol

Effect on reproductive function in sheep and cattle of inhibin immunoneutralization