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This study was achieved on 2 series of rabbits during the excretion of hard faeces and caecotrophes. Whatever the type of excretion the production and absorption of VFA seemed to take place in the caecum and the proximal colon only. Among the 3 VFA studied (acetic, propionic, butyric), butyric acid seemed to be more easily absorbed. This could be explained by the conversion of butyrate into ketone bodies which, by shifting its concentration gradient in favour of the intracellular medium, might activate its diffusion. Contrary to VFA, the production of plasma ketone bodies did not seem to depend on the butyric acid concentration of the material. Moreover, the good concordance beetween the percentage of the 3 VFA in the material and in the plasma suggested a possible absorption of VFA.

Concentration of VFA in the intestinal material and of VFA + ketone bodies in the veins of the large intestine in domestic rabbits