English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

To identify the risk factors of mortality for the coronavirus disease 19 (COVID-19) patients admitted to intensive care units (ICUs) through a retrospective analysis. The demographic, clinical, laboratory, and chest imaging data of patients admitted to the ICU of Huoshenshan Hospital from February 10 to April 10, 2020 were retrospectively analyzed. Student's t-test and Chi-square test were used to compare the continuous and categorical variables, respectively. The logistic regression model was employed to ascertain the risk factors of mortality. This retrospective study involved 123 patients, including 64 dead and 59 survivors. Among them, 57 people were tested for interleukin-6 (IL-6) (20 died and 37 survived). In all included patients, the oxygenation index (PaO 2 /FiO 2 ) was identified as an independent risk factor (odd ratio [OR] = 0.96, 95% confidence interval [CI]: 0.928–0.994,  p  = 0.021). The area under the curve (AUC) was 0.895 (95% CI: 0.826–0.943,  p  < 0.0001). Among the patients tested for IL-6, the PaO 2 /FiO 2  (OR = 0.955, 95%CI: 0.915–0.996,  p  = 0.032) and IL-6 (OR = 1.013, 95%CI: 1.001–1.025,  p  = 0.028) were identified as independent risk factors. The AUC was 0.9 (95% CI: 0.791–0.964,  p  < 0.0001) for IL-6 and 0.865 (95% CI: 0.748–0.941,  p  < 0.0001) for PaO 2 /FiO 2 . PaO 2 /FiO 2  and IL-6 could potentially serve as independent risk factors for predicting death in COVID-19 patients requiring intensive care.

PaO2/FiO2 and IL-6 are risk factors of mortality for intensive care COVID-19 patients