Open AccessAdvances in superresolution optical fluctuation imaging (SOFI)
Author(s) -
Thomas Dertinger,
Alessia Pallaoro,
Gary B. Braun,
Sonny Ly,
Ted A. Laurence,
Shimon Weiss
Publication year - 2013
Publication title -
quarterly reviews of biophysics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.613
H-Index - 97
eISSN - 1469-8994
pISSN - 0033-5835
DOI - 10.1017/s0033583513000036
Subject(s) - superresolution , optics , computer science , artificial intelligence , physics , image (mathematics)
We review the concept of superresolution optical fluctuation imaging (SOFI), discuss its attributes and trade-offs (in comparison with other superresolution methods), and present superresolved images taken on samples stained with quantum dots, organic dyes, and plasmonic metal nanoparticles. We also discuss the prospects of SOFI for live cell superresolution imaging and for imaging with other (non-fluorescent) contrasts.