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The investigation recorded in the present paper was undertaken as a corollary to the clinical trials with a new antityphoid serum, the results of which were recently published (Felix, 1935). Its object was to enquire into: (i) the occurrence of Vi antigen in strains of B. typhosus freshly isolated from cases of typhoid fever; (ii) the occurrence of Vi antibody in the blood serum of typhoid patients and convalescents.

The Occurrence of Typhoid Bacilli Containing Vi Antigen in Cases of Typhoid Fever and of Vi Antibody in their Sera