Open AccessThe uterine natural killer cell, cytotoxic T lymphocyte, and granulysin levels are elevated in the endometrium of women with nonstructural abnormal uterine bleeding
Author(s) -
Chidinma Iweha,
Amanda Graham,
Wei Cui,
Courtney Marsh,
Warren B. Nothnick
Publication year - 2022
Publication title -
fands science
Language(s) - English
Resource type - Journals
ISSN - 2666-335X
DOI - 10.1016/j.xfss.2022.04.003
Subject(s) - granulysin , stromal cell , cytotoxic t cell , endometrium , biology , immunohistochemistry , natural killer cell , endometrial biopsy , cd8 , medicine , endocrinology , andrology , immune system , immunology , cancer research , perforin , biochemistry , in vitro
To examine the expression of uterine natural killer (uNK) cells and cytotoxic T lymphocytes (CTLs) in endometrial biopsies from reproductive-age women with and without nonstructural abnormal uterine bleeding (AUB) and evaluate the expression of granulysin within these cell populations and potential modulation of matrix metalloproteinase (MMP) expression.