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How we experience events is critically dependent on our conceptual knowledge about them. Pain experience is no exception: it is shaped by expectations and beliefs, attentional focus, and social context [1–4]. Some painful events may even be associated with approach behavior and rewarding experiences. In these cases—whether it is habanero sauce on your eggs or the burn of your biceps as you curl a weight—nociceptive signals might even be perceived as pleasurable.

Multiple potential mechanisms for context effects on pain