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Hypothesis: Measuring rotational and translational Brownian motion of singlespherical particles reveals dissipations due to the interaction between theparticle and the environment. Experiments: In this article, we show experimentswhere the in-plane translational and two rotational drag coefficients of asingle spherical Brownian particle can be measured. These particle drags arefunctions of the particle size and the particle-wall distance, and of theviscous dissipations at play. We measure drag coefficients for Janus particlesclose to a solid wall and close to a lipid bilayer membrane. Findings: For aparticle close to wall, we show that according to hydrodynamic models,particlewall distance and particle size can be determined. For a particlepartially wrapped by lipid membranes, in absence of strong bindinginteractions, translational and rotational drags are significantly larger thanthe ones of non-wrapped particles. Beside the effect of the membrane viscosity,we show that dissipations in the deformed membrane cap region stronglycontribute to the drag coefficients.

Rotational and translational drags of a Janus particle close to a wall and a lipid membrane