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Kaposi's sarcoma (KS) is an unusual malignant vascular tumor principally affecting the skin of the lower extremities. It has four clinical varieties: classic, endemic, epidemic and iatrogenic.1 The latter is described mostly in organ transplant recipients receiving high-dose and/or long-term (9 to 23 months) immunosuppressive treatment.2 In addition, KS has been shown as a rare complication in inflammatory bowel diseases (IBD) that should be related to immunosuppression.3 Oral corticosteroids and immunomodulatory drugs, such as azathioprine (AZA) and 6-mercaptopurine (6-MP) are effective in Crohn's disease, however their use is limited …

Kaposi's sarcoma developing in a HIV-negative Crohn's disease patient shortly after azathioprine and corticosteroid treatment