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Dear Sir,We read with interest two meta-analyses recently published in this journal on the risk of postoperative complications following preoperative anti-TNF therapy in patients with Crohn's disease (CD).1,2 In the first meta-analysis,1 six studies assessing overall postoperative complications in CD patients (n = 1316) and seven studies assessing infectious postoperative complications in CD patients (n = 1699) were included. In the second meta-analysis,2 six studies involving 1159 CD patients were included. The majority of the studies included in the two studies1,2 were identical.In the first study, …

The risk of postoperative complications following preoperative anti-TNF therapy in patients with Crohn's disease: The need for prospective studies