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The present studies were undertaken to investigate if the activation of natriuretic peptide receptor-C (NPR-C) that has been shown to inhibit cell proliferation could also modulate the hypertrophic responses of vasoactive peptides in A10 vascular smooth muscle cells (VSMC).

Intracellular peptides of natriuretic peptide receptor-C inhibit vascular hypertrophy via Gqα/MAP kinase signaling pathways☆