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The clinical impact of the SIAPEC/SIE 2014 classification for thyroid cytology has been addressed in few studies that evaluated the malignancy rate and the relative prevalence of each category. No study analyzed its intra-observer and inter-observer reproducibility, so far.

Outcome and diagnostic reproducibility of the thyroid cytology “indeterminate categories” SIAPEC/SIE 2014 in a consecutive series of 302 cases