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Co-treatment of astragalin and quercetin (AGQC) significantly suppressed the ultraviolet (UV)-induced keratinocyte damage. Administration of AGQC in UV-irradiated mice reduced the histological skin alterations and the levels of chemokine (C-X-C motif) ligand 1 (CXCL1) and CXCL2. These results suggest that AGQC has a potential use as a compound for protection against UV-irradiated skin damage.

Protective effect of astragalin and quercetin on ultraviolet (UV)-irradiated damage in HaCaT cells and Balb/c mice