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Two new cyclic nonapeptides, named clausenlanins A (1) and B (2), were isolated from the roots and rhizomes of Clausena lansium. Their structures were elucidated as cyclo-(Gly 1 -L-Leu 2 -L-Ile 3 -L-Leu 4 -L-Leu 5 -L-Leu 6 -L-Leu 7 -L-Leu 8 -L-Leu 9 ) (1) and cyclo-(Gly 1 -L-Leu 2 -L-Val 3 -L-Leu 4 -L-Leu 5 -L-Leu 6 -L-Leu 7 -L-Leu 8 -L-Leu 9 ) (2) respectively on the basis of extensive spectroscopic analysis, particularly 2D NMR spectra taken at the temperature of 338 or 303 K and MS.

Clausenlanins A and B, Two Leucine-Rich Cyclic Nonapeptides from Clausena lansium