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Perihilar cholangiocarcinoma is the most common type of cholangiocarcinoma, accounting for approximately 60 % of cases, followed by the distal and then the intrahepatic forms. Although its surgical resection is technically demanding, many surgeons have adopted an aggressive approach to perihilar cholangiocarcinoma, as surgical resection is the only way to cure this intractable disease. In the past two decades, with advances in diagnostic and surgical techniques, the surgical outcomes and survival rates have gradually improved [1]. In this Editorial, we discuss the benefit of an aggressive surgical approach to perihilar cholangiocarcinoma, including combined vascular resection and hepatopancreatoduodenectomy.

Cutting edge of an aggressive surgical approach for perihilar cholangiocarcinoma