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The results from these studies indicate that glargine U300 was associated with a lower percentage of time in hypoglycaemia and that this lower risk of hypoglycaemia was in patients with low albumin concentrations. However, this study was limited by the lack of adjustment in starting insulin dose, the short study period to assess continuous glucose monitoring and the heterogeneous background therapies of the patient group.

diabetes therapy

Commentary to “Differential Effect of Hypoalbuminemia on Hypoglycemia on Type 2 Diabetes Patients Treated with Insulin Glargine 300 U/ml and Insulin Degludec” by Kawaguchi et al. Diabetes Therapy 2019