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Septal penetration causes collimator-dependent differences in the heart-to-mediastinum (H/M) ratio in 123 I-metaiodobenzylguanidine (MIBG) cardiac imaging. We investigated generally applicable methods to correct such differences.

journal of nuclear cardiology

Correction of collimator-dependent differences in the heart-to-mediastinum ratio in 123I-metaiodobenzylguanidine cardiac sympathetic imaging: Determination of conversion equations using point-source imaging