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3D tumor spheroid models are increasingly applied in secondary, cellbased drug testing due to certain therapy-relevant  in vivo -like characteristics. Automation of routine and delicate steps in spheroid culturing and processing, including the gentle well-to-well transfer of spheroids, facilitates spheroid-based assay standardization. Semi-automated workflows minimize experimental variations and are recommended in particular for combination treatment testing and long-term monitoring.

(Teil-)Automatisierung der liquid-overlay-Sphäroidkultivierung