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Morphological evaluation is currently considered the single most important predictive measure for assessing embryo quality. The aim of this study was to investigate whether cycles with at least one non-cleaved embryo (i.e., a 1-cell embryo on day 3) have different outcomes compared with cycles in which all embryos had cleaved by day 3.

Is the presence of a non-cleaved embryo on day 3 associated with poorer quality of the remaining embryos in the cohort?