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Two ensembles of climate simulations, one global and one regional, are used to investigate model errors and projected climate change in seasonal mean temperature and precipitation over South Asia. The global ensemble includes ten global climate models (GCMs). In the regional ensemble all ten GCMs are downscaled by a regional climate model—RCA4 over South Asia at 50 km resolution. Our focus is on the Indian Summer Monsoon season (June–August) and we show that RCA4 can reproduce, reduce or amplify large-scale GCM biases depending on regions and GCMs. However, the RCA4 bias pattern in precipitation is similar across the simulations, regardless of forcing GCM, indicating a strong RCA4 imprint on the simulated precipitation. For climate change, the results indicate, that RCA4 can change the signal projected by the GCM ensemble and its individual members. There are a few RCA4 simulations with a substantial reduction of projected warming by RCA4 compared to the driving GCMs and with a large regional increase in precipitation absent in the GCMs. We also found that in a number of subregions warm RCA4 biases are related to stronger warming and vice versa, while there is no such dependency in the GCM ensemble. Neither the GCM nor the RCA4 ensemble shows any significant dependency between projected changes and biases for precipitation. Our results implicate that using only RCMs and excluding GCMs, a commonly established approach, can significantly change the message on future regional climate change.

Contrasting regional and global climate simulations over South Asia