English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

We consider a population subdivided into two demes connected by migration inwhich selection acts in opposite direction. We explore the effects ofrecombination and migration on the maintenance of multilocus polymorphism, onlocal adaptation, and on differentiation by employing a deterministic modelwith genic selection on two linked diallelic loci (i.e., no dominance orepistasis). For the following cases, we characterize explicitly the possibleequilibrium configurations: weak, strong, highly asymmetric, andsuper-symmetric migration, no or weak recombination, and independent orstrongly recombining loci. For independent loci (linkage equilibrium) and forcompletely linked loci, we derive the possible bifurcation patterns asfunctions of the total migration rate, assuming all other parameters are fixedbut arbitrary. For these and other cases, we determine analytically the maximummigration rate below which a stable fully polymorphic equilibrium exists. Inthis case, differentiation and local adaptation are maintained. Their degree isquantified by a new multilocus version of $\Fst$ and by the migration load,respectively. In addition, we investigate the invasion conditions of locallybeneficial mutants and show that linkage to a locus that is already inmigration-selection balance facilitates invasion. Hence, loci of much smallereffect can invade than predicted by one-locus theory if linkage is sufficientlytight. We study how this minimum amount of linkage admitting invasion dependson the migration pattern. This suggests the emergence of clusters of locallybeneficial mutations, which may form `genomic islands of divergence'. Finally,the influence of linkage and two-way migration on the effective migration rateat a linked neutral locus is explored. Numerical work complements ouranalytical results.

The consequences of gene flow for local adaptation and differentiation: A two-locus two-deme model