English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The consensus algorithm for themanagement of type 2 diabetes mellitus was developed on behalf of the American Diabetes Association and the European Association for the Study of Diabetes approximately 1 year ago [1, 2]. This evidence-based algorithm was developed to help guide healthcare providers to choose the most appropriate treatment regimens from an everexpanding list of approved medications. The authors continue to endorse the major features of the algorithm, including the need to achieve and maintain glycaemia within or as close to the non-diabetic range as is safely possible; the initiation of lifestyle interventions and treatment with metformin at the time of diagnosis; the rapid addition of medications and transition to new regimens when target glycaemia is not achieved; and the early addition of insulin therapy in patients who do not meet target HbA1c levels. The availability of newly approved medications and the accrual of new clinical trial and other data should inform the algorithm. In this update we primarily address one important issue that has received much recent attention: our current understanding of the advantages and disadvantages of the thiazolidinediones. In addition, we have revised the original Table 1 to include the dipeptidylpeptidase-4 inhibitor sitagliptin, which was not approved by the US Food and Drug Administration at the time of our original publication (Table 1). Diabetologia (2008) 51:8–11 DOI 10.1007/s00125-007-0873-z

Management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy