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The existence of new vector-like quarks is often predicted by models of newphysics beyond the Standard Model, and the development of discovery strategiesat colliders is the object of an intense effort from the high-energy community.Our analysis aims at identifying the constraints on and peculiar signatures ofsimplified scenarios containing \textit{two} vector-like quark doublets mixingwith \textit{any} of the SM quark generations. This scenario is a necessaryingredient of a broad class of theoretically motivated constructions. We focuson the two charge $2/3$ states $t_{1,2}^\prime$ that, due to their peculiarmixing patterns, feature new production and decay modes that are not searchedfor at the LHC: single production of the heavier state can dominate over thelight one, while pair production via electroweak interactions overcomes the QCDone for masses at the TeV scale.

The LHC potential of Vector-like quark doublets