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Processes involving multi-input multi-step reaction cascades are used indeveloping novel biosensing, biocomputing, and decision making systems. Invarious applications different changes in responses of the constituentprocessing steps (reactions) in a cascade are desirable in order to allowcontrol of the system's response. Here we consider conversion of convexresponse to sigmoid by "intensity filtering," as well as "threshold filtering,"and we offer a general overview of this field of research. Specifically, wesurvey rate equation modelling that has been used for enzymatic reactions. Thisallows us to design modified biochemical processes as "network components" withresponses desirable in applications.

Modeling and Modifying Response of Biochemical Processes for Biocomputing and Biosensing Signal Processing