Open AccessGlutathione S-Transferase π Expression in Nasopharyngeal Cancer
Author(s) -
Anita Jayasurya,
Wai-Ming Yap,
Nam-Guan Tan,
B. T. G. Tan,
BoonHuat Bay
Publication year - 2002
Publication title -
archives of otolaryngology--head and neck surgery
Language(s) - English
Resource type - Journals
eISSN - 1538-361X
pISSN - 0886-4470
DOI - 10.1001/archotol.128.12.1396
Subject(s) - glutathione , glutathione s transferase , immunohistochemistry , nasopharyngeal carcinoma , biology , pathology , cancer , medicine , enzyme , immunology , biochemistry , radiation therapy
Glutathione S-transferase pi (GST-pi) is an enzyme that catalyzes the conjugation of electrophilic substrates and prevents oxidative damage. Although GST-pi expression has been analyzed in many cancers, the significance of GST-pi expression in nasopharyngeal cancer (NPC), a tumor with a high treatment failure rate, is still unclear.